ABSTRACT
Viral diseases are one of the major causes of mortality worldwide. The emergence of pandemics because of the Covid virus creates a dire need for an efficient mechanism to combat the disease. Viruses differ from other pathogenic infections; they render the host immune system vulnerable. One of the major challenges for developing antivirals is the resistance developed by the overuse of drugs, which is inevitable as most viral diseases require a large number of doses. Viral infection detection, prevention, and treatment have significantly benefitted from developing several innovative technologies in recent years. Nanotechnology has emerged as one of the most promising technologies because of its capacity to deal with viral infections efficiently and eradicate the lagging of conventional antiviral drugs. This review briefly presents an overview of the application of nanotechnology for viral therapy.
ABSTRACT
The COVID-19 illness is a highly contagious disease presently affecting more than 200 countries caused by the SARS-CoV-2 coronavirus (Severe Acute Respiratory Syndrome Coronavirus-2). Persons with diabetes mellitus (DM), severe obesity, cardiovascular disease, and hypertension are more likely to be infected with COVID-19 and are at a higher risk of death. The COVID-19 pandemic is overlapping the preexisting diabetes pandemic to produce fast and very vulnerable groups of COVID-19 and diabetes patients. Evidence relating to COVID-19 and diabetes is less but continues to emerge. In this context, we present evidence identified through rapid reviews. The current manuscript aims to provide information on diabetic patients suffering from COVID-19. Consequently, diabetic people have a higher susceptibility to severe SARS-CoV- 2 infections since defects in the glucose metabolism exacerbate the COVID-19 pathogenesis. After an extensive literature survey, it can come to an end that specific care is required for diabetes patients suffering from the COVID-19 virus. COVID-19 infection in diabetic patients may lead to loss of life if immediate care is not taken. This paper gives insight into the COVID-19 disease complications relevant to diabetes and emphasizes the current information and emerging concepts for SARS-CoV-2 infections in patients with DM.